Ku Shen / Bitter Root / Sophora
Sophora flavescens
Matrine and oxymatrine alkaloids from Ku Shen are extensively researched Chinese anti-cancer compounds. Matrine inhibits proliferation and induces apoptosis in liver, lung, colon, and breast cancer cells. Oxymatrine has been used in Chinese hospitals as an adjuvant to chemotherapy, showing reduced side effects and improved survival in liver cancer patients.
Medicinal Properties
Cancer Types Studied
Recommended Dosage
500–1000 mg standardised extract. Use under TCM practitioner supervision.
Preparations
TCM Formula Under Supervision
Ku Shen is typically used in TCM cancer formulas under practitioner guidance, not as a standalone supplement.
NIH / PubMed Research
Links open on PubMed (National Library of Medicine). Research is ongoing — results may not reflect clinical use.
Cautions & Interactions
- Toxic at high doses — strict adherence to therapeutic dose
- Use under qualified TCM/integrative oncology supervision
- May cause nausea and vomiting in some individuals
- Do not use in pregnancy
Related Herbs
Informational only. Not medical advice. Consult your healthcare provider before use.