iOnco
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Chaparro Amargo / Bitter Bush

Castela texana

Anti-parasitic Anti-cancerpreliminary evidence

Chaparro Amargo has been used in northern Mexican and Texas border folk medicine for centuries. Quassinoids isolated from Castela species — particularly glaucarubinone — show significant anti-leukaemic and anti-tumour activity in laboratory studies. The bitter compounds (quassinoids) interfere with protein synthesis in cancer cells. Also widely used as an anti-parasitic, particularly against amoebic dysentery, which may indirectly support cancer prevention through gut health.

Medicinal Properties

Anti-cancerAnti-parasiticAnti-amoebicAnti-inflammatoryAntimicrobialDigestive
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Cancer Types Studied

LeukemiaColonLiver

Recommended Dosage

Bark decoction: 1–2 tsp dried bark in 2 cups water, simmer 15 minutes. Drink 1 cup twice daily. Tincture: 2–4 ml in water three times daily.

Preparations

Bark Tea (Decoction)

1–2 tsp dried bark simmered in 500 ml water for 15–20 minutes. Strain. Drink 1 cup morning and evening. Very bitter taste.

Tincture

2–4 ml of 1:5 tincture in water, three times daily before meals. Used traditionally for digestive complaints and as a tonic.

NIH / PubMed Research

Links open on PubMed (National Library of Medicine). Research is ongoing — results may not reflect clinical use.

Cautions & Interactions

  • Very bitter — start with low doses
  • May cause nausea at high doses
  • Avoid in pregnancy
  • Limited clinical safety data — use under practitioner supervision
  • Do not confuse with other 'bitter bush' species

Informational only. Not medical advice. Consult your healthcare provider before use.