iOnco
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Cat's Claw / Uña de Gato

Uncaria tomentosa

Immune Modulatormoderate evidence

Oxindole alkaloids from Cat's Claw enhance NK cell and macrophage activity, inhibit tumour cell proliferation, and promote DNA repair. Studies show activity against colon, breast, and lung cancers. It also helps repair DNA damage caused by chemotherapy and radiation.

Medicinal Properties

ImmunomodulatoryAnti-tumourAnti-inflammatoryAntioxidantDNA repair
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Cancer Types Studied

ColonBreastLung

Recommended Dosage

300–600 mg standardised bark extract twice daily.

Preparations

Extract Capsules

300–600 mg standardised extract (TOA-free pentacyclic alkaloids) twice daily.

Tea

Simmer 1–2 tsp dried bark in 2 cups water for 15 min. Drink twice daily.

NIH / PubMed Research

Links open on PubMed (National Library of Medicine). Research is ongoing — results may not reflect clinical use.

Cautions & Interactions

  • Avoid in autoimmune conditions
  • May interact with immunosuppressants and blood thinners
  • Avoid in pregnancy and breastfeeding
  • Look for pentacyclic alkaloid (POA) products, not tetracyclic (TOA)

Informational only. Not medical advice. Consult your healthcare provider before use.