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Trikatu / Three Spice Formula

Piper longum + Piper nigrum + Zingiber officinale

Bioavailability enhancermoderate evidence

Trikatu is an Ayurvedic formula of three spices (Long Pepper, Black Pepper, and Ginger) used to dramatically enhance absorption of all co-administered herbs and supplements. Piperine from both peppers and shogaols/gingerols from ginger collectively enhance bioavailability by 30–2000%. It is the archetypal Ayurvedic 'bio-enhancer' — taken with virtually every other Ayurvedic anti-cancer formula.

Medicinal Properties

Bioavailability enhancerAnti-tumourDigestive fireAnti-inflammatoryThermogenic

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Cancer Types Studied

All Cancers

Recommended Dosage

250–500 mg Trikatu powder 2–3x daily with other herbs.

Preparations

Trikatu Powder with Other Herbs

250–500 mg Trikatu powder mixed with or taken alongside other Ayurvedic cancer formulas. Standard Ayurvedic practice — enhances all concurrent herb absorption.

NIH / PubMed Research

PMID 20657536Trikatu piperine bio-enhancement of herbal compounds

Links open on PubMed (National Library of Medicine). Research is ongoing — results may not reflect clinical use.

Cautions & Interactions

May irritate stomach lining — avoid in acute gastritis or ulcers
Increases absorption of ALL medications — consult doctor if on pharmaceutical drugs
Avoid in pregnancy in medicinal doses
Thermogenic — may worsen inflammatory conditions temporarily during detox