iOnco
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Ashwagandha

Withania somnifera

Adaptogenmoderate evidence

Withaferin A, the primary withanolide in Ashwagandha, induces apoptosis in breast, colon, prostate, and lung cancer cells, inhibits proteasome activity, and disrupts cytoskeletal proteins. Beyond direct anti-tumour effects, ashwagandha reduces cortisol, improves sleep, reduces cancer-related fatigue, and supports immune function during treatment.

Medicinal Properties

AdaptogenicAnti-stressImmunomodulatoryAnti-tumourNeuroprotectiveAnti-fatigue
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Cancer Types Studied

BreastColonProstateLung

Recommended Dosage

300–600 mg standardised root extract (2.5–5% withanolides) twice daily. Or 3–6 g root powder in warm milk daily.

Preparations

KSM-66 / Sensoril Capsules

300–600 mg standardised extract twice daily. KSM-66 and Sensoril are the most clinically studied forms.

Ashwagandha Milk

1 tsp root powder in warm milk with cardamom and honey at bedtime. Supports sleep, builds stamina.

NIH / PubMed Research

Links open on PubMed (National Library of Medicine). Research is ongoing — results may not reflect clinical use.

Cautions & Interactions

  • May lower thyroid hormone — caution in hypothyroid patients
  • Can lower blood pressure — monitor with antihypertensives
  • Avoid in pregnancy
  • Do not use in autoimmune conditions without supervision

Informational only. Not medical advice. Consult your healthcare provider before use.